| CAMPEONATO CLAUSURA 2022 | ||||
| 1º Fecha | ||||
| 1-jul-2022 | Santa Cruz | Santa Cruz | 3 | Romero (3) |
| Universitario Sucre | 0 | |||
| 1-jul-2022 | Sucre | Independiente Petrolero | 1 | Cristaldo (P) |
| Universitario de Vinto | 1 | Oliveira | ||
| 2-jul-2022 | Cochabamba | Jorge Wilstermann | 2 | Willie, Añez |
| Atletico Palmaflor | 1 | Wesley da Silva | ||
| 2-jul-2022 | Tarija | Real Tomayapo | 2 | Chajtur (2) |
| Royal Pari | 1 | Garcia | ||
| 2-jul-2022 | Santa Cruz | Oriente Petrolero | 3 | Sanchez, Suarez, Roca |
| The Strongest | 0 | |||
| 3-jul-2022 | Potosi | Nacional Potosi | 3 | Tobar (2), Alvarez (P) |
| Aurora | 1 | Pinto | ||
| 3-jul-2022 | Montero | Guabira | 0 | |
| Always Ready | 1 | Medina | ||
| 3-jul-2022 | Santa Cruz | Blooming | 2 | Jefferson da Silva, Rafinha |
| Bolivar | 1 | Chico | ||
| 2º Fecha | ||||
| 5-jul-2022 | Cochabamba | Atletico Palmaflor | 2 | Igor Soares, Pedraza |
| Real Tomayapo | 1 | Garzon | ||
| 5-jul-2022 | Santa Cruz | Royal Pari | 3 | Bejarano, Alvarez, Perez (P) |
| Independiente Petrolero | 2 | Cristaldo, Buter | ||
| 5-jul-2022 | Sucre | Universitario Sucre | 2 | Ovejero (2) |
| Oriente Petrolero | 0 | |||
| 6-jul-2022 | El Alto | Always Ready | 2 | Riquelme (2, 1P) |
| Nacional Potosi | 1 | Tobar | ||
| 6-jul-2022 | Cochabamba | Aurora | 1 | Pinto |
| Guabira | 0 | |||
| 6-jul-2022 | Santa Cruz | Blooming | 5 | Rafinha, Spenhay, Arismendi, Jefferson da Silva (2) |
| Santa Cruz | 1 | Jean | ||
| 7-jul-2022 | Cochabamba | Universitario de Vinto | 0 | |
| Bolivar | 1 | Miranda | ||
| 3-ago-2022 | La Paz | The Strongest | 2 | Triverio, Reinoso (P) |
| Jorge Wilstermann | 0 | |||
| 3º Fecha | ||||
| 8-jul-2022 | Santa Cruz | Oriente Petrolero | 0 | |
| Royal Pari | 1 | Perez | ||
| 9-jul-2022 | Santa Cruz | Santa Cruz | 0 | |
| Atletico Palmaflor | 0 | |||
| 9-jul-2022 | Cochabamba | Aurora | 1 | Maidana |
| Always Ready | 1 | Arce | ||
| 9-jul-2022 | Sucre | Oriente Petrolero | 3 | Martinez, Godoy, Campos |
| Blooming | 0 | |||
| 10-jul-2022 | Potosi | Nacional Potosi | 1 | Tobar |
| The Strongest | 5 | Gomez, Triverio (2), Arrascaita, Sotomayor | ||
| 10-jul-2022 | Tarija | Real Tomayapo | 0 | |
| Bolivar | 2 | Chico, Bruno Savio | ||
| 10-jul-2022 | Cochabamba | Jorge Wilstermann | 2 | Willie (2, 1P) |
| Universitario de Vinto | 0 | |||
| 11-jul-2022 | Montero | Guabira | 5 | Hurtado, Ruiz Diaz, Robles (2), Montenegro |
| Universitario Sucre | 0 | |||
| 4º Fecha | ||||
| 15-jul-2022 | Cochabamba | Jorge Wilstermann | 2 | Echeverria, Castillo |
| Guabira | 2 | Supayabe, Montenegro | ||
| 15-jul-2022 | Tarija | Real Tomayapo | 1 | Chajtur |
| Santa Cruz | 2 | Romero, Jean | ||
| 16-jul-2022 | Santa Cruz | Royal Pari | 2 | Amoroso, Garcia |
| Nacional Potosi | 2 | Tobar (2) | ||
| 16-jul-2022 | Sucre | Independiente Petrolero | 1 | Martinez |
| Bolivar | 4 | Chico (2), Miranda, Rodriguez | ||
| 16-jul-2022 | Cochabamba | Atletico Palmaflor | 1 | Erverson (P) |
| Aurora | 2 | Torrico, Mune | ||
| 17-jul-2022 | Sucre | Universitario Sucre | 0 | |
| The Strongest | 3 | Ursino (2), Arrascaita | ||
| 17-jul-2022 | El Alto | Always Ready | 3 | Ramallo, Cristaldo, Enoumba |
| Universitario de Vinto | 0 | |||
| 17-jul-2022 | Santa Cruz | Blooming | 2 | Arismendi, Herrera (P) |
| Oriente Petrolero | 2 | Suarez, Dorrego | ||
| 5º Fecha | ||||
| 23-jul-2022 | Santa Cruz | Royal Pari | 2 | Correa (2, 1P) |
| Atletico Palmaflor | 2 | Wesley da Silva (2) | ||
| 23-jul-2022 | Santa Cruz | Santa Cruz | 2 | Jean, Garcia (P) |
| Oriente Petrolero | 1 | Suarez (P) | ||
| 23-jul-2022 | Montero | Guabira | 2 | Melean, Ruiz Diaz |
| Nacional Potosi | 1 | Tobar (P) | ||
| 24-jul-2022 | El Alto | Always Ready | 5 | Ramallo, Riquelme (2, 1P), Borja, Valda |
| Real Tomayapo | 0 | |||
| 24-jul-2022 | La Paz | The Strongest | 4 | Esparza, Prost, Triverio, Gomez |
| Aurora | 0 | |||
| 24-jul-2022 | Sucre | Independiente Petrolero | 2 | Godoy, Diaz |
| Universitario Sucre | 0 | |||
| 25-jul-2022 | La Paz | Bolivar | 3 | Chico, Melgar, Uzeda |
| Jorge Wilstermann | 0 | |||
| 3-ago-2022 | Cochabamba | Universitario de Vinto | 2 | Huayhuata (P), Jardin |
| Blooming | 2 | Arismendi, Sagredo | ||
| 6º Fecha | ||||
| 26-jul-2022 | Potosi | Nacional Potosi | 3 | Mancilla, Valencia, Navarro |
| Santa Cruz | 1 | Jean | ||
| 26-jul-2022 | Santa Cruz | Oriente Petrolero | 4 | Ribera, Roca, Rojas, Suarez |
| Guabira | 1 | Hurtado (P) | ||
| 27-jul-2022 | Tarija | Real Tomayapo | 4 | Albarracin, Jeffinho, Chajtur (2) |
| Universitario de Vinto | 0 | |||
| 27-jul-2022 | Sucre | Universitario Sucre | 1 | Romat |
| Royal Pari | 0 | |||
| 27-jul-2022 | La Paz | The Strongest | 4 | Arrascaita, Torres, Castillo, Saucedo |
| Always Ready | 2 | Rambal, Valda | ||
| 28-jul-2022 | La Paz | Bolivar | 2 | Villamil, Abrego |
| Atletico Palmaflor | 2 | Wesley da Silva, Abastoflor | ||
| 28-jul-2022 | Santa Cruz | Blooming | 0 | |
| Jorge Wilstermann | 1 | Bianconi | ||
| 29-jul-2022 | Cochabamba | Aurora | 1 | Blanco |
| Independiene Petrolero | 0 | |||
| 7º Fecha | ||||
| 30-jul-2022 | El Alto | Always Ready | 4 | Brun (A), Riquelme (2), Arce (P) |
| Universitario Sucre | 0 | |||
| 30-jul-2022 | Cochabamba | Universitario de Vinto | 0 | |
| Guabira | 1 | Figueroa | ||
| 31-jul-2022 | Cochabamba | Jorge Wilstermann | 0 | |
| Real Tomayapo | 2 | Jeffinho, Echeverria (A) | ||
| 31-jul-2022 | La Paz | Bolivar | 0 | |
| The Strongest | 4 | Haquin (A), Martins (A), Triverio, Chura | ||
| 31-jul-2022 | Santa Cruz | Royal Pari | 3 | Amoroso (3) |
| Blooming | 1 | Navarro | ||
| 1-ago-2022 | Santa Cruz | Santa Cruz | 1 | Romero |
| Aurora | 1 | Torrico | ||
| 1-ago-2022 | Cochabamba | Atletico Palmaflor | 0 | |
| Nacional Potosi | 1 | Alvarez | ||
| 1-ago-2022 | Sucre | Independiente Petrolero | 1 | Ribera (A) |
| Oriente Petrolero | 2 | Roca, Suarez | ||
| 8º Fecha | ||||
| 5-ago-2022 | El Alto | Always Ready | 4 | Algarañaz, Cristaldo, Reyes, Valda |
| Santa Cruz | 0 | |||
| 5-ago-2022 | Santa Cruz | Oriente Petrolero | 0 | |
| Atletico Palmaflor | 0 | |||
| 6-ago-2022 | Sucre | Independiente Petrolero | 4 | Ramirez (2), Velasquez, Santos |
| Jorge Wilstermann | 1 | Moriceau (A) | ||
| 6-ago-2022 | Montero | Guabira | 1 | Leal |
| Royal Pari | 4 | |||
| 6-ago-2022 | Santa Cruz | Blooming | 1 | Rafinha |
| Real Tomayapo | 0 | |||
| 7-ago-2022 | Potosi | Nacional Potosi | 2 | Alvarez, Andia |
| Bolivar | 1 | Melgar | ||
| 7-ago-2022 | La Paz | The Strongest | 3 | Sotomayor, Arrascaita, Castillo |
| Universitario de Vinto | 2 | Huayhuata (P), Vargas | ||
| 7-ago-2022 | Cochabamba | Aurora | 1 | Blanco |
| Universitario Sucre | 1 | Ovejero | ||
| 9º Fecha | ||||
| 9-ago-2022 | Tarija | Real Tomayapo | 1 | Aleman |
| Independiente Petrolero | 0 | |||
| 9-ago-2022 | Cochabamba | Jorge Wilstermann | 0 | |
| Oriente Petrolero | 1 | Rojas | ||
| 10-ago-2022 | Santa Cruz | Santa Cruz | 0 | |
| The Strongest | 3 | Prost, Ortega, Saucedo | ||
| 10-ago-2022 | Cochabamba | Atletico Palmaflor | 2 | Terrazas, Erverson |
| Blooming | 1 | Carrasco | ||
| 10-ago-2022 | La Paz | Bolivar | 3 | Rocha, Bruno Savio (2) |
| Guabira | 0 | |||
| 11-ago-2022 | Cochabamba | Universitario de Vinto | 0 | |
| Aurora | 3 | Vaca, Pinto (2) | ||
| 11-ago-2022 | Sucre | Universitario Sucre | 0 | |
| Nacional Potosi | 1 | Guerra | ||
| 28-sep-2022 | Santa Cruz | Royal Pari | 0 | |
| Always Ready | 2 | Enoumba, Riquelme | ||
| 10º Fecha | ||||
| 13-ago-2022 | Santa Cruz | Santa Cruz | 1 | Romero |
| Bolivar | 2 | Melgar, Bruno Savio | ||
| 13-ago-2022 | La Paz | The Strongest | 1 | Sotomayor |
| Atletico Palmaflor | 1 | Abastoflor | ||
| 13-ago-2022 | Montero | Guabira | 1 | Alaniz (P) |
| Independiente Petrolero | 1 | Ramirez | ||
| 14-ago-2022 | Potosi | Nacional Potosi | 1 | Torrico |
| Jorge Wilstermann | 0 | |||
| 14-ago-2022 | Sucre | Universitario Sucre | 2 | Calero, Ovejero |
| Universitario de Vinto | 1 | Huayhuata (P) | ||
| 14-ago-2022 | Santa Cruz | Oriente Petrolero | 3 | Vaca, Sanchez, Ribera |
| Real Tomayapo | 0 | |||
| 15-ago-2022 | El Alto | Always Ready | 5 | Riquelme (3), Algarañaz, Ramallo |
| Blooming | 0 | |||
| 15-ago-2022 | Cochabamba | Aurora | 2 | Mune, Barboza |
| Royal Pari | 1 | Garcia | ||
| 11º Fecha | ||||
| 19-ago-2022 | Cochabamba | Universitario de Vinto | 3 | Huayhuata, Ndoutoumo, Vargas |
| Nacional Potosi | 1 | Alvarez | ||
| 19-ago-2022 | Tarija | Real Tomayapo | 3 | Barrios, Jeffinho, Caicedo |
| Aurora | 0 | |||
| 19-ago-2022 | Sucre | Independiente Petrolero | 1 | Godoy |
| Santa Cruz | 0 | |||
| 20-ago-2022 | Santa Cruz | Royal Pari | 0 | |
| The Strongest | 2 | Prost, Ortega (P) | ||
| 20-ago-2022 | La Paz | Bolivar | 1 | Fernandez |
| Oriente Petrolero | 0 | |||
| 20-ago-2022 | Cochabamba | Jorge Wilstermann | 5 | Castellon (2), Romat (A), Vargas, Fernandez |
| Universitario Sucre | 1 | Romat | ||
| 21-ago-2022 | Cochabamba | Atletico Palmaflor | 2 | Terrazas, Wesley da Silva |
| Always Ready | 4 | Alaca (A), Algarañaz, Riquelme, Medina | ||
| 21-ago-2022 | Santa Cruz | Blooming | 1 | Rafinha |
| Guabira | 3 | Ruiz Diaz, Melean, Leal | ||
| 12º Fecha | ||||
| 23-ago-2022 | Santa Cruz | Santa Cruz | 2 | Romero, Suarez |
| Royal Pari | 1 | Alvarez | ||
| 23-ago-2022 | Santa Cruz | Oriente Petrolero | 0 | |
| Universitario de Vinto | 0 | |||
| 23-ago-2022 | Cochabamba | Aurora | 1 | Blanco |
| Bolivar | 4 | Sagredo, Barboza (A), Francisco Aragão, Justiniano | ||
| 24-ago-2022 | Montero | Guabira | 2 | Leal (2, 1P) |
| Real Tomayapo | 1 | Chajtur (P) | ||
| 24-ago-2022 | Sucre | Universitario Sucre | 2 | Prudencio, Ovejero |
| Atletico Palmaflor | 1 | Wesley da Silva (P) | ||
| 24-ago-2022 | La Paz | The Strongest | 3 | Carrasco (A), Prost, Triverio |
| Blooming | 1 | Rafinha | ||
| 25-ago-2022 | El Alto | Always Ready | 2 | Valda, Cabrera |
| Jorge Wilstermann | 1 | Serginho | ||
| 25-ago-2022 | Potosi | Nacional Potosi | 3 | Barbery, Alvarez, Guerra |
| Independiente Petrolero | 2 | Cristaldo (2, 1P) | ||
| 13º Fecha | ||||
| 26-ago-2022 | Cochabamba | Universitario de Vinto | 2 | Ndoutoumo, Llano |
| Santa Cruz | 0 | |||
| 26-ago-2022 | La Paz | Bolivar | 3 | Francisco Aragao, Bejarano, Bruno Savio |
| Royal Pari | 0 | |||
| 27-ago-2022 | Cochabamba | Atletico Palmaflor | 2 | Ramallo, Abastoflor (P) |
| Guabira | 0 | |||
| 27-ago-2022 | Tarija | Real Tomayapo | 0 | |
| The Strongest | 1 | Prost | ||
| 27-ago-2022 | Santa Cruz | Blooming | 1 | Arano |
| Universitario Sucre | 1 | Prudencio | ||
| 28-ago-2022 | Cochabamba | Jorge Wilstermann | 2 | Castellon, Vargas |
| Aurora | 0 | |||
| 28-ago-2022 | Sucre | Independiente Petrolero | 1 | Thomaz Santos |
| Always Ready | 1 | Riquelme | ||
| 28-ago-2022 | Santa Cruz | Oriente Petrolero | 4 | Suarez, Tobar (A), Dorrego, Roca |
| Nacional Potosi | 0 | |||
| 14º Fecha | ||||
| 30-ago-2022 | Santa Cruz | Royal Pari | 2 | Cepeda, Correa |
| Universitario de Vinto | 1 | Huayhuata (P) | ||
| 30-ago-2022 | La Paz | The Strongest | 2 | Amarilla (A), Triverio |
| Guabira | 3 | Ruiz Diaz (2), Alaniz | ||
| 30-ago-2022 | Sucre | Universitario Sucre | 2 | Suarez, Gallegos |
| Bolivar | 3 | Rodriguez, Bruno Savio, Francisco Aragao | ||
| 31-ago-2022 | El Alto | Always Ready | 3 | Reyes, Galindo, Riquelme (P) |
| Oriente Petrolero | 0 | |||
| 31-ago-2022 | Cochabamba | Atletico Palmaflor | 2 | Wesley da Silva (P), Ramallo |
| Independiente Petrolero | 1 | Thomaz Santos | ||
| 31-ago-2022 | Potosi | Nacional Potosi | 2 | Tobar (2, 1P) |
| Real Tomayapo | 1 | Caicedo | ||
| 1-sep-2022 | Santa Cruz | Santa Cruz | 0 | |
| Jorge Wilstermann | 0 | |||
| 1-sep-2022 | Cochabamba | Aurora | 1 | Zenteno |
| Blooming | 0 | |||
| 15º Fecha | ||||
| 3-sep-2022 | Sucre | Independiente Petrolero | 1 | Buter |
| The Strongest | 1 | Ursino | ||
| 3-sep-2022 | Cochabamba | Universitario de Vinto | 1 | Ali |
| Atletico Palmaflor | 1 | Gomez | ||
| 3-sep-2022 | Tarija | Real Tomayapo | 1 | Maldonado |
| Universitario Sucre | 1 | Ardian | ||
| 4-sep-2022 | Montero | Guabira | 2 | Ruiz Diaz, Alaniz (P) |
| Santa Cruz | 1 | Pariani | ||
| 4-sep-2022 | La Paz | Bolivar | 3 | Bejarano, Fernandez, Bruno Savio |
| Always Ready | 0 | |||
| 4-sep-2022 | Santa Cruz | Blooming | 4 | Jefferson da Silva (2), Sanchez, Rafinha |
| Nacional Potosi | 0 | |||
| 5-sep-2022 | Cochabamba | Jorge Wilstermann | 2 | Echeverria, Willie |
| Royal Pari | 1 | Correa | ||
| 5-sep-2022 | Santa Cruz | Oriente Petrolero | 2 | Sanchez (P), Correa |
| Aurora | 1 | Maygua | ||
| 16º Fecha | ||||
| 6-sep-2022 | Cochabamba | Universitario de Vinto | 4 | Vallejos, Vila, Llano, Ndoutoumo |
| Independiente Petrolero | 1 | Buter | ||
| 7-sep-2022 | El Alto | Always Ready | 2 | Riquelme (2) |
| Guabira | 1 | Alaniz | ||
| 7-sep-2022 | Sucre | Universitario Sucre | 3 | Ovejero (2), Ardian |
| Santa Cruz | 1 | Romero | ||
| 7-sep-2022 | La Paz | Bolivar | 3 | Francisco da Costa, Bejarano (P), Villamil |
| Blooming | 0 | |||
| 8-sep-2022 | Santa Cruz | Royal Pari | 0 | |
| Real Tomayapo | 1 | Caicedo | ||
| 8-sep-2022 | Cochabamba | Atletico Palmaflor | 1 | Savane |
| Jorge Wilstermann | 1 | Serginho (P) | ||
| 8-sep-2022 | La Paz | The Strongest | 2 | Reinoso (P), Triverio |
| Oriente Petrolero | 1 | Gonzales | ||
| 9-sep-2022 | Cochabamba | Aurora | 1 | Torrico |
| Nacional Potosi | 5 | Navarro, Tobar, Alvarez, Pavia, Mancilla | ||
| 17º Fecha | ||||
| 10-sep-2022 | Santa Cruz | Santa Cruz | 1 | Garcia |
| Blooming | 3 | Herrera, Suarez (A), Garzon | ||
| 10-sep-2022 | La Paz | Bolivar | 2 | Cesar Martins, Rodriguez |
| Universitario de Vinto | 0 | |||
| 11-sep-2022 | Sucre | Independiente Petrolero | 3 | Cristaldo (2), Thomaz Santos |
| Royal Pari | 0 | |||
| 11-sep-2022 | Cochabamba | Jorge Wilstermann | 0 | |
| The Strongest | 3 | Prost (2), Ortega | ||
| 11-sep-2022 | Santa Cruz | Oriente Petrolero | 1 | Caire (P) |
| Universitario Sucre | 0 | |||
| 12-sep-2022 | Montero | Guabira | 1 | Figueroa |
| Aurora | 1 | Maygua | ||
| 12-sep-2022 | Tarija | Real Tomayapo | 2 | Chajtur, Arizala (P) |
| Atletico Palmaflor | 2 | Terrazas, Gomez | ||
| 12-sep-2022 | Potosi | Nacional Potosi | 1 | Alvarez |
| Always Ready | 1 | Riquelme (P) | ||
| 18º Fecha | ||||
| 16-sep-2022 | Cochabamba | Atletico Palmaflor | 4 | Savane (2), Gomez (2) |
| Santa Cruz | 0 | |||
| 16-sep-2022 | La Paz | The Strongest | 1 | Reinoso |
| Nacional Potosi | 1 | Tobar | ||
| 17-sep-2022 | El Alto | Always Ready | 0 | |
| Aurora | 1 | Aranibar | ||
| 17-sep-2022 | Sucre | Universitario Sucre | 1 | Romat |
| Guabira | 1 | Melean | ||
| 17-sep-2022 | Santa Cruz | Blooming | 1 | Garzon |
| Independiente Petrolero | 0 | |||
| 18-sep-2022 | Cochabamba | Universitario de Vinto | 0 | |
| Jorge Wilstermann | 0 | |||
| 18-sep-2022 | La Paz | Bolivar | 4 | Da Costa (2), Fernandez, Bejarano (P) |
| Real Tomayapo | 1 | Olguin | ||
| 18-sep-2022 | Santa Cruz | Royal Pari | 1 | Garcia |
| Oriente Petrolero | 0 | |||
| 19º Fecha | ||||
| 30-sep-2022 | Santa Cruz | Santa Cruz | 1 | Mina |
| Real Tomayapo | 1 | Pascua | ||
| 30-sep-2022 | Montero | Guabira | 1 | Alaniz |
| Jorge Wilstermann | 1 | Menacho (P) | ||
| 1-oct-2002 | Potosi | Nacional Potosi | 1 | Galain |
| Royal Pari | 1 | |||
| 1-oct-2022 | Cochabamba | Aurora | 0 | |
| Atletico Palmaflor | 0 | |||
| 1-oct-2022 | La Paz | Bolivar | 0 | |
| Independiente Petrolero | 0 | |||
| 2-oct-2022 | Cochabamba | Universitario de Vinto | 1 | Genesis |
| Always Ready | 2 | Riquelme, Reyes | ||
| 2-oct-2022 | La Paz | The Strongest | 1 | Triverio (P) |
| Universitario Sucre | 0 | |||
| 2-oct-2022 | Santa Cruz | Oriente Petrolero | 1 | Correa |
| Blooming | 0 | |||
| 20º Fecha | ||||
| 4-oct-2022 | Cochabamba | Atletico Palmaflor | 1 | Abastoflor (P) |
| Royal Pari | 1 | Garcia | ||
| 4-oct-2022 | Potosi | Nacional Potosi | 3 | Alvarez (2), Tobar |
| Guabira | 1 | Ruiz Diaz | ||
| 4-oct-2022 | Cochabamba | Jorge Wilstermann | 1 | Serginho (P) |
| Bolivar | 1 | Bejarano (P) | ||
| 5-oct-2022 | Tarija | Real Tomayapo | 0 | |
| Always Ready | 3 | Chumacero, Adrian, Riquelme | ||
| 5-oct-2022 | Cochabamba | Aurora | 0 | |
| The Strongest | 0 | |||
| 5-oct-2022 | Santa Cruz | Oriente Petrolero | 3 | Suarez (2), Correa |
| Santa Cruz | 1 | Romero | ||
| 6-oct-2022 | Santa Cruz | Blooming | 0 | |
| Universitario de Vinto | 0 | |||
| 6-oct-2022 | Sucre | Universitario Sucre | 2 | Maldonado, Prudencio |
| Independiente Petrolero | 1 | Cristaldo | ||
| 21º Fecha | ||||
| 7-oct-2022 | Cochabamba | Atletico Palmaflor | 1 | Terrazas (P) |
| Bolivar | 1 | Rodriguez | ||
| 8-oct-2022 | Santa Cruz | Santa Cruz | 2 | Romero, Lizio |
| Nacional Potosi | 1 | Mancilla | ||
| 8-oct-2022 | El Alto | Always Ready | 1 | Enoumba |
| The Strongest | 3 | Ortega (P), Chura, Sotomayor | ||
| 9-oct-2022 | Cochabamba | Universitario de Vinto | 1 | Vallejos |
| Real Tomayapo | 1 | Rioja | ||
| 9-oct-2022 | Santa Cruz | Royal Pari | 3 | Correa, Orfano, Amoroso |
| Universitario Sucre | 1 | Suarez | ||
| 9-oct-2022 | Montero | Guabira | 2 | Figueroa, Robles |
| Oriente Petrolero | 1 | Gonzales | ||
| 9-oct-2022 | Cochabamba | Jorge Wilstermann | 1 | Osorio (P) |
| Blooming | 0 | |||
| 10-oct-2022 | Sucre | Independiente Petrolero | 1 | Campos |
| Aurora | 1 | Blanco (P) | ||
| 22º Fecha | ||||
| 11-oct-2022 | Potosi | Nacional Potosi | 6 | C. Alvarez (2), W. Alvarez (3), Romay |
| Atletico Palmaflor | 1 | Erverson | ||
| 12-oct-2022 | Montero | Guabira | 1 | Robles |
| Universitario de Vinto | 0 | |||
| 12-oct-2022 | Sucre | Universitario Sucre | 1 | Calero |
| Always Ready | 3 | Cristaldo, Riquelme, Adrian | ||
| 12-oct-2022 | La Paz | The Strongest | 4 | Benegas, Ortega (P), Torres, Triverio (P) |
| Bolivar | 4 | Rodriguez (2), Villamil, Martins | ||
| 12-oct-2022 | Santa Cruz | Blooming | 0 | |
| Royal Pari | 0 | |||
| 13-oct-2022 | Santa Cruz | Oriente Petrolero | 3 | Dorrego (P), Caire (P), Vaca |
| Independiente Petrolero | 3 | Chiatti, Cristaldo (2, 1P) | ||
| 13-oct-2022 | Cochabamba | Aurora | 1 | Blanco (P) |
| Santa Cruz | 2 | Romero (2) | ||
| 13-oct-2022 | Santa Cruz | Real Tomayapo | 1 | Valencia |
| Jorge Wilstermann | 0 | |||
| 23º Fecha | ||||
| 15-oct-2022 | Cochabamba | Universitario de Vinto | 2 | Viscarra (A), Llano |
| The Strongest | 1 | Chura | ||
| 15-oct-2022 | La Paz | Bolivar | 3 | Lima, Andia (A), Sagredo |
| Nacional Potosi | 1 | Romay | ||
| 15-oct-2022 | Santa Cruz | Royal Pari | 3 | Garcia, Correa, Alvarez |
| Guabira | 2 | Quiroga, Alaniz | ||
| 16-oct-2022 | Cochabamba | Atletico Palmaflor | 2 | Bahebeck, Pedraza |
| Oriente Petrolero | 2 | Cabrera (P), Rojas | ||
| 16-oct-2022 | Santa Cruz | Santa Cruz | 1 | Lizio |
| Always Ready | 0 | |||
| 16-oct-2022 | Sucre | Universitario Sucre | 1 | Prudencio |
| Aurora | 1 | Blanco (P) | ||
| 17-oct-2022 | Cochabamba | Jorge Wilstermann | 1 | Castellon |
| Independiente Petrolero | 3 | Cristaldo (3, 2P) | ||
| 17-oct-2022 | Tarija | Real Tomayapo | 1 | Arizala |
| Blooming | 1 | Arano | ||
| 24º Fecha | ||||
| 19-oct-2022 | El Alto | Always Ready | 1 | Paniagua |
| Royal Pari | 0 | |||
| 19-oct-2022 | La Paz | The Strongest | 5 | Prost (2), Ortega (2, 1P), Ursino |
| Santa Cruz | 2 | Lizio, Mercado | ||
| 19-oct-2022 | Potosi | Nacional Potosi | 3 | Tobar (3) |
| Universitario Sucre | 2 | Ovejero, Prudencio (P) | ||
| 19-oct-2022 | Montero | Guabira | 2 | Robles, Leal |
| Bolivar | 1 | Bejarano | ||
| 20-oct-2022 | Cochabamba | Aurora | 0 | |
| Universitario de Vinto | 2 | Huayhuata (2, 1P) | ||
| 20-oct-2022 | Santa Cruz | Blooming | 1 | Rafinha |
| Atletico Palmaflor | 0 | |||
| 20-oct-2022 | Sucre | Independiente Petrolero | 1 | Ramirez |
| Real Tomayapo | 0 | |||
| 21-oct-2022 | Santa Cruz | Oriente Petrolero | 2 | Ribera, Correa |
| Jorge Wilstermann | 1 | Castellon | ||